in Fort Wayne, IN
Platelet-rich fibrin (PRF) offers a deeply restorative way to support your body’s own healing without synthetic ingredients. At Lilivy, we utilize PRF to address early signs of aging, reduce dark circles, enhance skin texture, stimulate hair regrowth, and promote overall tissue healing.
This next-generation platelet concentrate uses a simple blood draw to isolate your body’s most beneficial components: white blood cells, red blood cells, stem cells, and concentrated growth factors, all suspended in a soft fibrin matrix. When injected or applied topically, PRF stimulates collagen production, improves circulation, and accelerates the healing process.
Unlike platelet-rich plasma (PRP), PRF is spun more gently and without the use of anticoagulants, allowing for a slow and sustained release of healing properties over time. It’s a natural solution backed by science and one of the most advanced treatment modalities we offer for skin and hair restoration.
PRF is a second-generation platelet concentrate derived from your own peripheral blood. After a simple blood draw, the sample is spun at a low speed to separate key blood components, including platelet concentrate, white blood cells, red blood cells, and fibrin. This process produces a platelet-rich fibrin matrix rich in growth factors, such as platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF), which support wound healing, collagen stimulation, and tissue regeneration.
Unlike platelet-rich plasma (PRP), PRF contains no additives or anticoagulants, such as calcium chloride. This allows for the gradual release of growth factors, promoting a longer-lasting effect. Additionally, PRF forms a soft fibrin clot that acts as a scaffold for cellular repair.
PRF can be used on its own or in combination with other treatment modalities, such as microneedling, laser therapy, or dermal fillers. Because it’s derived entirely from your own blood, it’s considered an autologous concentrate, making it one of the safest regenerative therapies available today.
PRF treatment begins with a simple blood draw, typically from your arm. The collected blood is placed into a specialized tube and spun in a centrifuge at a low speed, isolating white blood cells, platelets, and other components involved in the healing process.
Once processed, the resulting platelet-rich fibrin matrix is separated and prepared for use. Depending on your goals, PRF may be:
The process takes about 45–60 minutes. Most clients describe the injections as tolerable, with minimal discomfort.
PRF supports skin rejuvenation, hair restoration, and soft tissue healing. It's particularly effective in treating:
By improving blood circulation and stimulating collagen production, PRF enables the skin to function and regenerate more efficiently, particularly in areas that are challenging to treat with conventional therapies.
PRF is most commonly used on:
Because PRF relies on your own biological material, it’s safe for use in most soft tissue areas and well-tolerated even in sensitive zones.
The benefits of PRF treatment extend beyond cosmetic results. While the most visible changes often include smoother skin and a more youthful appearance, the true value lies in the skin’s improved function and healing capacity.
Because the process involves no additives, PRF is especially beneficial for patients who are sensitive to other treatment modalities or those seeking a more natural, regenerative option.
Benefits include:
Enhanced collagen production
Longer-lasting results compared to PRP
No synthetic chemicals or foreign materials
Supports wound healing and tissue repair
Minimizes the risk of allergic reaction
Improves skin texture and tightness
Restores volume and radiance over time
Most healthy adults are good candidates for PRF. It's ideal for clients looking to:
PRF may not be appropriate if you have an active infection, a blood clotting disorder, or certain chronic medical conditions. We’ll discuss your full health history during your consultation to ensure a safe and effective plan.
Recovery after a PRF treatment is minimal. You may notice mild swelling, redness, or bruising at the injection site, particularly in sensitive areas such as the under-eye area or scalp. These effects typically subside within a few days.
Because PRF supports the wound healing process, many clients experience a quicker recovery when it’s used alongside other services, such as microneedling, laser resurfacing, or dermal fillers. You can return to normal activities shortly after treatment, with a few simple aftercare guidelines to support the healing process.
Results from PRF appear gradually, with improvements typically becoming noticeable within 2 to 4 weeks. Because PRF encourages your body to heal and rebuild on its own, results take time, but they’re also more subtle, natural, and long-lasting.
Clients often notice:
Depending on your goals, a series of 2 to 4 treatments spaced 4 to 6 weeks apart may be recommended. Maintenance sessions may be scheduled every 6 to 12 months to provide continued support.
Lilivy offers a physician-led, boutique approach to regenerative care. Under the guidance of Dr. Stephanie Sublett, our aesthetic specialists are trained in advanced PRF protocols and integrate this treatment with your overall wellness and aesthetic goals.
Every PRF treatment is carefully tailored to complement your goals, schedule, and comfort level. Whether you’re addressing early signs of aging, hair thinning, or sexual health, we’ll guide you every step of the way.
This is care that respects your biology, honors your pace, and gives your body what it needs to heal on its own terms.
PRF is often considered an advancement over PRP because it contains more growth factors, white blood cells, and a fibrin matrix that releases healing properties more gradually. This leads to longer-lasting benefits with less risk of inflammation.
A simple blood draw is taken and spun in a specialized centrifuge. The slower spin speed preserves beneficial components, such as stem cells, white blood cells, and platelets, without the need for the anticoagulants used to create PRP.
Yes. Because PRF is made entirely from your own blood, there’s no risk of allergic reaction or rejection. It’s one of the most natural regenerative treatments available.
Yes. PRF can enhance healing and prolong results when used in conjunction with fillers. It’s often used in tandem for a more balanced, gradual effect.
When injected into the scalp, PRF stimulates blood vessels, hair follicles, and tissue regeneration, helping to improve hair thickness and reduce shedding over time.
Most clients benefit from a series of 2–4 sessions, depending on their skin or hair goals. We’ll create a personalized treatment plan during your consultation.